“The
findings, from researchers at the University of Kansas, add to a growing body
of research showing that exercise is good for the brain at any stage of life,
even for seniors who already have Alzheimer’s or other forms of dementia. For
the study, published in the journal PLOS One, the scientists studied 68 older
men and women in the early stages of Alzheimer’s disease. Their average age was
about 73.
“Half
were enrolled in a rigorous, six-month exercise program that involved brisk
walking and similar aerobic activity. Volunteers participated in three to five
exercise sessions a week, building up to a total of at least 150 minutes of
exercise a week. The exercises were done at 16 YMCA’s in the Kansas City area and
supervised and monitored by trained exercise specialists.
“The
other half were enrolled in a less rigorous exercise program that involved
mainly stretching and toning exercises but little aerobic activity.
Participants engaged in activities like core strengthening exercises,
resistance band training, and modified tai chi and yoga programs, activities
that kept their heart rates under 100 beats per minute. All the participants
were given periodic tests of memory and thinking skills during the six months
of the study. They also underwent MRI scans to assess any changes in the brain.
“At
the end of six months, those in the exercise group could generally move and get
around better; their caregivers noted that they were more efficient in carrying
out day-to-day activities like dressing and feeding themselves. They also
tended to show less decline in memory skills than those in the stretching group.
Benefits were modest, however, and not everyone in the exercise group showed
cognitive improvements.
“Brain
scans also revealed that those who had gotten aerobic exercise also tended to
have less shrinkage in the hippocampus, a part of the brain critical for
memory. The hippocampus is among the first areas of the brain typically
affected by Alzheimer’s disease, and less brain shrinkage is associated with
preservation of memory and thinking skills.
“Studying
the impact of exercising continues to be a promising area of Alzheimer’s
disease research. Other studies have shown that regular walking and physical
activity may help to ward off Alzheimer’s in old age. People who exercise
regularly in middle age, for example, are at lower risk of developing Alzheimer’s
in old age. Other studies have shown that those with mild cognitive impairment,
a form of memory loss that often precedes dementia, were less likely to
progress to full-blown Alzheimer’s if they got regular exercise.
“These
latest findings suggest that activities like walking can have benefits at any
age, even in seniors who already have Alzheimer’s disease. Exercise helps to
generate new cells in the hippocampus, earlier research has found. Regular
physical activity is also critical for blood vessel health, including the blood
vessels that nourish the brain. So regardless of age, it’s probably a wise idea
to take a walk, or two, or three.”
By ALZinfo.org,
The Alzheimer’s Information Site. Reviewed by Marc Flajolet, Ph.D., Fisher
Center for Alzheimer’s Research Foundation at The Rockefeller University.
Source:
Jill K. Morris, Eric D. Vidoni, David K. Johnson, et al: “Aerobic exercise for
Alzheimer’s disease: A randomized controlled pilot trial.” PLOS One, February
10, 2017
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