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Sunday, April 30, 2017
Saturday, April 29, 2017
"Playing a musical instrument during adulthood is significantly associated with reduced risk of cognitive impairment and dementia"
How playing an instrument benefits your brain - Anita Collins:
Playing a Musical Instrument as a Protective Factor against Dementia and Cognitive Impairment: A Population-Based Twin Study:
“Playing and learning a musical instrument has been shown to benefit cognitive development and health during younger life, but what about learning and playing an instrument as an adult?
Playing a Musical Instrument as a Protective Factor against Dementia and Cognitive Impairment: A Population-Based Twin Study:
“Playing and learning a musical instrument has been shown to benefit cognitive development and health during younger life, but what about learning and playing an instrument as an adult?
“Until now, the effect of playing an instrument as a leisure
activity and dementia risk has not been thoroughly investigated… [R]esearch
published in the International Journal of Alzheimer’s Disease suggests
that playing a musical instrument during adulthood is significantly associated
with reduced risk of cognitive impairment and dementia.
“The researcher’s analyzed data from 157 sets of twin’s
participating in a Swedish study, known as HARMONY. This study is unique as it only
recruited for sets of twins where one twin had been diagnosed with a form of
dementia or a cognitive impairment, and the other twin had not. Conducting the
research on twins allowed the researchers to control for a large number of
genetic and environmental factors. This meant the research could determine risk
factors that were unique to the twin with dementia, as well as protective
factors exclusive to the healthy twin.
“The focus of this paper was to explore whether playing a
musical instrument in later life was a protective factor for dementia. All
participants completed a lifestyle questionnaire, which included questions
about their experience of playing a musical instrument. These questions
included whether the participant played new and/or familiar music, their frequency
of playing, and whether she/he was still playing at time of assessment or
stopped playing at a specific age. It is important to note that none of the
participants identified themselves as a professional musician.
“Of the 157 sets of twins (i.e. 314 individuals), 31
individuals identified that they played a musical instrument. When they delved
further into these 31 musicians, 27 were found to be cognitively healthy, while
four had dementia. So when the researchers analyzed this specific group of
twins (controlling for gender, education, and physical activity) they found
that those participants who played an instrument in older adulthood had a 64%
lower likelihood of developing a cognitive impairment or dementia.
“This result provides more evidence that learning a new
hobby (such as a musical instrument) may be able to stimulate your brain and
reduce your risk of dementia.”
Sources/Research
Article:
International Journal of Alzheimer’s disease - http://www.hindawi.com/journals/ijad/2014/836748/
Friday, April 28, 2017
TRS Report from Bob Lyons, Trustee (via Marge Sucansky at the IRTA Area 3 Conference)
The
average retired teacher in Illinois as of June last year received $54,252, but
received little or no social security. In Fiscal Year 2016, the state
contributed $3.742 billion to the TRS fund; for FY 2017, it is $3.986 billion,
and for FY 2018 it will be $4.565 billion. The size of the increase is
greater because the TRS Board lowered the expected rate of return from 7.5% to 7.0%,
which forces the state to make up the difference going forward. The
difference added $421 million to the state's contribution for next
year...
Based
on where we were at the end of the year 2016:
FYTD
CYTD 3 5
10 20 years
%
Return for TRS
5.01
8.33 5.88 9.53 5.55
7.54
The
total number of annuitants is 118,483, which includes retired teachers,
survivors, and disabled. As of December 31, 2016, the total actuarial
accrued liability was $124.2 billion; the TRS fund was at $45.3 billion, which
meant we had an unfunded actuarial liability of $71.4 billion and were funded
at 36.5%. An estimate today for the TRS fund is approximately $48 billion
or at 38.6%...
Under
existing law, statutorily-required general funds pension contributions grew to
$6.9 billion in FY2017 from $1.6 billion in FY2008. Debt service on
previously issued bonds increased to $1.6 billion from $467 million during the
same period, bringing total pension-related payments to $8.5 billion from $2.1
billion. The total state contribution to pensions is just over 25% of all
that it takes in for the fiscal year.
|
Sugar and Artificially-Sweetened Beverages and the Risks of Incident Stroke and Dementia
A Prospective Cohort
Study:
Matthew
P. Pase, Jayandra J. Himali, Alexa S. Beiser, Hugo J. Aparicio, Claudia L.
Satizabal, Ramachandran S. Vasan, Sudha Seshadri, Paul F. Jacques
Originally published
April 20, 2017
Abstract:
Background
and Purpose— Sugar
and artificially-sweetened beverage intake have been linked to cardio-metabolic
risk factors, which increase the risk of cerebrovascular disease and dementia.
We examined whether sugar- or artificially sweetened beverage consumption was
associated with the prospective risks of incident stroke or dementia in the
community-based Framingham Heart Study Offspring cohort.
Methods—
We studied
2888 participants aged >45 years for incident stroke (mean age 62 [SD, 9]
years; 45% men) and 1484 participants aged >60 years for incident dementia
(mean age 69 [SD, 6] years; 46% men). Beverage intake was quantified using a
food-frequency questionnaire at cohort examinations 5 (1991–1995), 6
(1995–1998), and 7 (1998–2001). We quantified recent consumption at examination
7 and cumulative consumption by averaging across examinations. Surveillance for
incident events commenced at examination 7 and continued for 10 years. We
observed 97 cases of incident stroke (82 ischemic) and 81 cases of incident
dementia (63 consistent with Alzheimer’s disease).
Results—
After
adjustments for age, sex, education (for analysis of dementia), caloric intake,
diet quality, physical activity, and smoking, higher recent and higher
cumulative intake of artificially sweetened soft drinks were associated with an
increased risk of ischemic stroke, all-cause dementia, and Alzheimer’s disease
dementia. When comparing daily cumulative intake to 0 per week (reference), the
hazard ratios were 2.96 (95% confidence interval, 1.26–6.97) for ischemic
stroke and 2.89 (95% confidence interval, 1.18–7.07) for Alzheimer’s disease.
Sugar-sweetened beverages were not associated with stroke or dementia.
Conclusions—
Artificially-sweetened
soft drink consumption was associated with a higher risk of stroke and
dementia.
To
Download the study, click here.
Thursday, April 27, 2017
Genes Associated With Resilience against Brain Pathology Identified (from Rush University Medical Center)
Genes
help cognition withstand damage in brain from Alzheimer’s, Parkinson’s:
“The pathologies
(damage) in the brain that stroke, Alzheimer’s disease and other neurological
conditions cause in older adults only partially explain the memory loss,
reduced reasoning ability and other cognitive impairments that result from
these conditions. Little is known about why the effects of brain pathology vary
among people who develop it.
“Now researchers have
discovered two genes, known as UNC5C and ENC1, that are associated with aging
individuals having better memory and brain function than would be expected,
given the amount of pathologies that accumulated in their brains. They reported
their findings in an article published today [April 25, 2017] in the journal PLOS Medicine.
“‘Most of the cognitive
loss that we experience in older age remains unexplained. Certain individuals
are very resistant to the pathologies of the aging brain, while others may be
particularly vulnerable,’ says study senior investigator David Bennett, MD, who directs the Rush Alzheimer’s Disease Center.
“These potentially
damaging pathologies include the buildup of harmful proteins known as amyloid
plaques and neurofibrillary tangles that occur in Alzheimer’s disease; the protein deposits known
as Lewy bodies that accompany Parkinson’s disease and Lewy body dementia; and
the death of massive amounts of brain cells caused by stroke.
“Identifying genes that
contribute to resistance to these and other brain pathologies could provide
researchers with new targets for developing medications that would enhance the
brains of aging adults to resist Alzheimer’s disease and other neurological
conditions, Bennett says.
Study used genetic analysis of 979 organ donors’
brain tissue:
“The researchers drew
on a vast trove of data, including genetic analyses, generated by two ongoing
long-term studies of aging based at Rush University Medical Center, which
includes study participants’ donation of their brains for research after their
death. These participants were tested annually to measure their cognitive
function, allowing for a comparison of the decrease in cognitive function with
the development of any pathology found when their brains were autopsied after
their deaths.
“Using this information
for 979 participants, the researchers assessed how much each person’s thinking
ability withstood the development of memory loss despite the accumulation of
brain pathology – in other words, how resilient they were to pathology. Then
they conducted a complex, multiple step analysis ‘to identify segments of the
human genome (i.e, genes) that help us to maintain cognitive function in the
face of advancing age and disease,’ explains study senior investigator Philip
De Jager, MD, PhD, professor of neurology at Columbia University Medical
Center.
“The innovative
approach combined an analysis of the human genome – the complete set of genes
in a person — with an evaluation of the epigenome — changes to DNA that helps
determine which genes can be ‘read’ so its protein is made. Epigenome in part
reflects how our brain responds to life experiences and exposures to
environmental factors.
“The analysis
identified UNC5C and ENC1 as being associated with cognitive resilience. In
addition, the researchers found that TMEM106B — a gene whose presence
previously had been identified as possibly protecting against age-related
frontotemporal lobar degeneration — also may play a role in brain resilience.
“‘These genes should be
studied further to expand our understanding of molecular mechanisms relevant to
cognitive resilience that could be translated into prognostic and therapeutic
tools for dementia prevention,’ the researchers write in the paper’s summary.
“The PLOS Medicine article presenting the
study’s findings is titled ‘Identification of genes associated with
dissociation of cognitive performance and neuropathological burden: Multistep
analysis of genetic, epigenetic, and transcriptional data.’ The study included
researchers at Rush University Medical Center, the Broad Institute, Brigham and
Women’s Hospital/Harvard Medical School, Columbia University Medical Center,
The Illinois Institute of Technology, the T.H. Chan School of Public Health and
the University of British Columbia.
“The work was supported
by grants from the National Institute on Aging. The investigators are indebted
to the study participants.”
This article is from Rush University Medical Center, Chicago, Illinois
Tuesday, April 25, 2017
This Sickening Reason Is Why You Should Never Buy Food from Jimmy John's Again! by Lara Starr
“Some
companies should be BOYCOTTED for various reasons. JIMMY JOHN'S is ABSOLUTELY
one of them. And no, this isn’t about many of the issues people are always
talking about when it comes to working for Jimmy John’s either, like the fact
that they force their sick employees to work for fear of losing their jobs. And
if they get fired or quit, they’re not allowed to work at any sandwich shop or
restaurant within a three mile radius of a Jimmy John’s either… (Read about all that here).
“No. Today we’re talking about the owner, Jimmy
John Liautaud himself, who is a complete… psychopath who loves to spend your
sandwich money on killing endangered animals in Africa.
“Jimmy
comes to South Africa (and sometimes Namibia or Botswana) quite frequently.
When he does, he easily drops more than a quarter million dollars on a single
trophy hunt. Like on this trip, when he butchered an EXTREMELY ENDANGERED
female BLACK RHINO. She was the very last black rhino in the Mangetti National
Park. Buying her just to kill her and take her horn (as a trophy) cost Jimmy
over $350,000 dollars. He doesn’t seem to mind spending that much though does
he? Just look how happy he is!
“…So
how does it work? Well, usually the animals are lured from a national park on
to private property. Trophy hunters will leave out bait, play the sounds of
other animals to lure them in, or a few other tactics to find their animal
victims. Canned hunting is even worse. It is the ‘shooting fish in a barrel’
version of trophy hunting. The animals are often hand raised so they are tame
and don’t run away. They leave food out for them one day, then some coward
creeps up and shoots them with a high powered bow or rifle. Sometimes they
don’t even have to creep. Sometimes they just shoot them from the back of a
truck then go back to drinking their Gin & Tonic like it was just a bit of
harmless fun…
“Part
of the infuriating thing about this behavior is the fact that people like Jimmy
have the audacity to call themselves ‘conservationists’ and claim that their
trophy hunts benefit conservation and local communities. Real conservationists
give their time and money without insisting on killing something in return…
“Jimmy is absolutely full of crap when he
claims that trophy hunting funds conservation, feeds starving villages or
keeps the ecosystem in balance by keeping animal numbers down. Those are 100%
lies perpetuated by the trophy hunting industry, and they’re easily disproved.
“It
is well known here that trophy hunting funds less than 2% of our conservation
efforts in South Africa. Normal tourism (as in shooting animals with cameras
only) raises over 15x more money for conservation than any form of trophy
hunting in Africa does, without brutally killing anything. Most people who do
trophy or canned hunting like this are only fattening the wallets of wealthy
game farm owners who only care to protect their own animals from poachers
coming on their property. This does nothing to protect animals in the ‘wild’
national parks where most endangered animals live.
“As
for feeding locals, 9 times out of 10 the meat from a trophy hunt (especially
if it’s a large animal) is left in the dirt for the scavengers because they can’t
be bothered to move the body or process it. Plus, the locals here don’t eat
lions, rhinos or elephants anyway. They eat fish, chicken, pork and beef like
most people around the world do...
“Ecosystems
need to be better protected, especially fragile ones that are so out of balance
due to over hunting, poaching and habitat loss, like the African bush… In case
there is some doubt about… conservation, you can read a much more in depth
explanation here: The Myth of Trophy Hunting as Conservation”
From
This Sickening Reason Is Why You Should Never Buy Food from Jimmy John’s Again! by Lara Starr, Journalist, Activist
and Researcher
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